Yves Bourbonnais Selected Research

Elafin

8/2007	Characterization of human pre-elafin mutants: full antipeptidase activity is essential to preserve lung tissue integrity in experimental emphysema.
7/2006	Increased local levels of granulocyte colony-stimulating factor are associated with the beneficial effect of pre-elafin (SKALP/trappin-2/WAP3) in experimental emphysema.
2/2006	Proteins with whey-acidic-protein motifs and cancer.
7/2002	Anti-inflammatory effect of pre-elafin in lipopolysaccharide-induced acute lung inflammation.
2/2002	Inhibition of human neutrophil elastase-induced acute lung injury in hamsters by recombinant human pre-elafin (trappin-2).

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Yves Bourbonnais Research Topics

Disease

3	Emphysema 08/2007 - 05/2003
1	Carcinogenesis 02/2006
1	Neoplasms (Cancer) 02/2006
1	Rheumatoid Arthritis 05/2003
1	Cystic Fibrosis (Mucoviscidosis) 05/2003
1	Inflammation (Inflammations) 05/2003
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 05/2003
1	Reperfusion Injury 05/2003
1	Chronic Obstructive Pulmonary Disease (COPD) 05/2003
1	Pneumonia (Pneumonitis) 07/2002
1	Lung Diseases (Lung Disease) 02/2002
1	Lung Injury 02/2002
1	Acute Lung Injury 02/2002
1	Hemorrhage 02/2002

Drug/Important Bio-Agent (IBA)

5	ElafinIBA 08/2007 - 02/2002
4	Pancreatic Elastase (Elastase)IBA 08/2007 - 02/2002
3	Leukocyte Elastase (Neutrophil Elastase)IBA 08/2007 - 02/2002
2	Peptide Hydrolases (Proteases)FDA Link 02/2006 - 05/2003
1	Myeloblastin (Proteinase 3)IBA 08/2007
1	EnzymesIBA 08/2007
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 07/2006
1	Proteins (Proteins, Gene)FDA Link 02/2006
1	LipopolysaccharidesIBA 07/2002
1	Hemoglobins (Hemoglobin)IBA 02/2002